1
to be in charge of;to manage;to direct;to administer;to preside over
市長は市政を司る。
The mayor administers the affairs of the city.
2
to rule;to govern;to control
Other forms
掌る 【つかさどる】 (rarely used kanji form) · 主る 【つかさどる】 (search-only kanji form) · 司どる 【つかさどる】 (search-only kanji form)