1
since then;from that time;ever since
それ以来彼のうわさは聞いていない。
He has never been heard of since.
1
since;henceforth
１９８８年以来トムに会っていません。
I haven't seen Tom since 1988.
2
ever since
Other forms
已来 【いらい】 (rarely used kanji form)