如何
1
(depending on) how;(depending on) what;nature (of)
after a noun (+ の)
天候のいかんにかかわらず駅へ迎えに参ります。
Rain or shine, I will come to meet you at the station.
2
what is ...?;how is ...?;what will be ...?
at sentence end
Other forms
奈何 【いかん】 (rarely used kanji form)