1
beginning;start;first step
とても魅力的な人に初めて会って、話の糸口を見つけるのは、たいていかなり難しいものだ。
People usually find it very difficult to break the ice when they meet someone extremely attractive for the first time.
2
clue;lead;hint
わずかなヒントを糸口にして、正しいこたえを見つけた。
He took a slight hint as the start and found the correct answer.
3
thread end
1
Itoguchi
Other forms
緒 【いとぐち】 · 絲口 【いとぐち】 (word containing out-dated kanji or kanji usage)