1
to operate (e.g. a machine);to handle;to manage;to control;to maneuver;to steer
2
to have a good command of (a language);to play proficiently (of a musical instrument)
あの通訳は５か国語を自由に操る。
That interpreter is a master of five languages.
3
to work (a puppet);to pull the strings of a puppet
4
to manipulate (a person, public opinion, etc.);to pull the strings;to control from the shadows;to mastermind
儲けようとする投機筋に操られているのです。
It's being manipulated by investors trying to make it rich.