1
low-lying part of a city (usu. containing shops, factories, etc.)
彼女は下町で生まれ育った。
She was born and brought up on the backstreets.
2
Shitamachi (low-lying area of eastern Tokyo near Tokyo Bay, incl. Asakusa, Shitaya, Kanda, Fukugawa, Honjo, Nihonbashi, Kyobashi and surrounds)
See also:
山の手 (やまのて)
1
Shitamachi